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68% of American Adults Are Omega-3 Deficient. You're Probably One of Them.

Sustainably sourced from wild-caught small fish. Extracted without harsh chemicals. 1,856mg total Omega-3s per serving delivered in the triglyceride form your body actually absorbs.

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68% of American Adults Are Omega-3 Deficient. You're Probably One of Them.

Experience the freshest, cleanest omega-3 on the market—sustainably sourced, potent, and free from unnecessary additives.

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20 million+ views

@hormonespecialist

1.5 million+ followers

20 million+ views

@hormonespecialist

1.5 million+ followers

20 million+ views

@hormonespecialist

1.5 million+ followers

20 million+ views

@hormonespecialist

1.5 million+ followers

20 million+ views

@hormonespecialist

1.5 million+ followers

20 million+ views

@hormonespecialist

1.5 million+ followers

What Omega-3 Does For Your Body

Click Each Body Part To Learn How Omega-3 May Help Support It. ⬇
All Sources Cited Towards Bottom Of Page.

 

Eases Everyday Movement*

EPA and DHA support your body’s natural inflammation response, which directly impacts joint comfort and mobility. Research shows omega-3 supplementation may help relieve joint discomfort and support joint function.

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Strengthens Your Defenses*

Omega-3s may support healthy immune cell function and your body’s natural inflammatory response. A well-regulated immune system responds appropriately to threats without overreacting, and EPA and DHA may help maintain that balance.

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Learn More About Omega-3 Directly From Layne

  • What are Omega-3's?

  • Where do Omega-3's come from?

  • What is BDNF?

  • Taking Omega-3's over time.

    The Omega-3 Gap: What the Research Shows

    0%

    of U.S. adults have omega-3 levels below the threshold recommended by Dietary Guidelines for Americans.*

    0%

    of American children have inadequate omega-3 blood levels—making deficiency a generational problem.*

    0%

    of Americans have an Omega-3 Index in the optimal cardioprotective range. Most hover around 4-5%.*

    0%

    of U.S. adults have omega-3 levels below the threshold recommended by Dietary Guidelines for Americans.*

    0%

    of American children have inadequate omega-3 blood levels—making deficiency a generational problem.*

    0%

    of Americans have an Omega-3 Index in the optimal cardioprotective range. Most hover around 4-5%.*

    Why Are Most Americans Falling Short?

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    Omega-3 Formulated for Results. Not Marketing Claims.

    Most fish oil supplements cut corners you can't see. Low-quality extraction. Plastic packaging that leaches chemicals. The cheaper ethyl ester form that absorbs poorly.

    We built this formula differently—because your results depend on what's actually in the capsule.

    High-Potency Formula

    1,856mg Total Omega-3s Per Serving
    Each 4-capsule serving delivers 1,140mg EPA and 584mg DHA—the clinically relevant doses shown in research to meaningfully raise your Omega-3 Index.

    Triglyceride Form

    The Form Your Body Actually Absorbs
    Unlike cheaper ethyl ester fish oils, our omega-3s come in the natural triglyceride form—research shows significantly better absorption and bioavailability. [3]

    Supercritical CO2 Extraction

    No Harsh Chemicals. No Solvents. No Residue.
    We use supercritical CO2 extraction at low temperatures to concentrate EPA and DHA while preserving their integrity. The result: pure oil without chemical contamination.

    Glass Bottle Packaging

    Protected From Plastic Leaching
    Omega-3s are sensitive to oxidation and contamination. Glass bottles prevent chemical leaching and maintain freshness from our facility to your shelf.

    Sustainably Sourced

    Wild-Caught Anchovies, Sardines & Young Mackerel
    Small fish, low on the food chain, mean lower heavy metal accumulation. Responsibly harvested to protect marine ecosystems.

    Third-Party Tested

    Every Batch Verified for Purity & Potency
    Independent testing confirms accurate label claims and screens for heavy metals, oxidation, and contaminants. No surprises.

    Save 20% + Free Shipping

    verified 60 Day Satisfaction Guarantee

    Omega-3 Formulated for Results. Not Marketing Claims.

    Most fish oil supplements cut corners you can't see. Low-quality extraction. Plastic packaging that leaches chemicals. The cheaper ethyl ester form that absorbs poorly.

    We built this formula differently—because your results depend on what's actually in the capsule.

    High-Potency Formula

    1,856mg Total Omega-3s Per Serving
    Each 4-capsule serving delivers 1,140mg EPA and 584mg DHA—the clinically relevant doses shown in research to meaningfully raise your Omega-3 Index.

    Triglyceride Form

    Supercritical CO2 Extraction

    No Harsh Chemicals. No Solvents. No Residue.
    We use supercritical CO2 extraction at low temperatures to concentrate EPA and DHA while preserving their integrity. The result: pure oil without chemical contamination.

    Save 20% + Free Shipping

    verified 60 Day Satisfaction Guarantee

    Glass Bottle Packaging

    Protected From Plastic Leaching
    Omega-3s are sensitive to oxidation and contamination. Glass bottles prevent chemical leaching and maintain freshness from our facility to your shelf.

    Sustainably Sourced

    Wild-Caught Anchovies, Sardines & Young Mackerel
    Small fish, low on the food chain, mean lower heavy metal accumulation. Responsibly harvested to protect marine ecosystems.

    Third-Party Tested

    Every Batch Verified for Purity & Potency
    Independent testing confirms accurate label claims and screens for heavy metals, oxidation, and contaminants. No surprises.

    Not All Fish Oil Is Created Equal

    Feature Hormone Specialist Store Brand Bargain Brand
    Total Omega-3 1,856mg 600–1,000mg 300–600mg
    EPA 1,140mg 180–400mg 90–180mg
    DHA 584mg 120–300mg 60–120mg
    Form Triglyceride(better absorption) Ethyl Ester Ethyl Ester
    Extraction Method Supercritical CO2(no chemicals) Chemical Solvents Unknown
    Packaging Glass Bottle Plastic Plastic
    Third-Party Tested ✓ ~ ✕
    Heavy Metal Screening ✓ ~ ✕
    Sustainable Sourcing ✓ ✕ ✕
    No Artificial Additives ✓ ✕ ✕
    Swipe to compare →

    Why does this matter?

    A meta-analysis of 40 randomized trials found that cardiovascular benefits of EPA and DHA are dose-dependent, and as covered in Section 10, the triglyceride form absorbs more efficiently than ethyl esters. A standard fish oil capsule typically provides around 300 mg of combined EPA and DHA — meaning you may need more capsules to reach an effective daily dose compared to a concentrated formula. Scan the QR code on every bottle label for lot-specific certificates of analysis.*

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    local_shipping Ships within 24 Hours Mon-Fri

    eco Clean & Pure Ingredients

    verified 60-Day Money Back Guarantee

    Our Omega-3 is formulated by a registered pharmacist using the triglyceride form for better absorption, supercritical CO2 extraction for purity, and glass bottle packaging to protect freshness. Every batch is third-party tested.

    High EPA Purified Fish Oil (as Triglycerides), Mixed Natural Tocopherols, Purified Water, Gelatin (bovine), Non-GMO Vegetable Glycerin. Contains: Fish (Anchovies, Mackerel, Sardines). Free from gluten, dairy, soy, and artificial additives.

    Take 4 capsules daily, ideally just before your largest meal. Though not required, taking with food can enhance absorption and minimizes any chance of aftertaste.

    Individual responses vary. Research shows that the Omega-3 Index typically approaches optimal levels after 8–12 weeks of consistent supplementation, depending on your starting levels and daily dose. Many of the benefits measured in clinical studies — such as changes in cardiovascular markers, inflammatory biomarkers, and lipid profiles — develop gradually over this period.*

    Our extraction and purification process is designed to minimize fishy aftertaste. Taking capsules with food further reduces any chance of reflux. Most people experience none.

    We manufacture in small batches to help ensure freshness, so our product doesn’t sit on a shelf for extended periods of time.

    Orders ship within 1 business day and typically arrive in 1-4 days. We offer a 60-day money-back guarantee— if you're not satisfied, contact us for a full refund.

    Customer avatar (Verified reviewer)
    Layne Kilpatrick,Co-Founder | R. Ph.
    "In my opinion, Omega-3 Fish Oil is probably the most important supplement available over-the-counter. It is one of the most studied molecules in all of medicine. This product is the result of careful formulation to contain minimal ingredients with demonstrated safety and activity."

    eco
    Sustainable

    Our Omega-3 Fish Oil is sustainably sourced from wild-caught anchovies, young mackerel, and sardines.

    lab_panel
    Third-Party Tested

    Each batch is independently tested for purity, potency, and heavy metals, delivering trusted quality in every capsule.

    Layne's Guarantee

    I formulated this Omega-3 because I couldn't find one I trusted for my own family. If you're not completely satisfied with the quality, the results, or anything else—just let us know within 60 days and we'll refund every penny. No hassle, no hoops, no return required. I stand behind this product because I take it myself, every single day.

    - Layne Kilpatrick, R. Ph., Co-Founder

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     4.85/5 Rating | 17,000+ Satisfied Customers

    Reviews From Our Customers

    Questions Before You Start

    Take 4 capsules daily, ideally just before your largest meal. Though not required, taking with food can enhance absorption and minimizes any chance of aftertaste.

    Our product specifically minimizes fishy aftertaste. This is due largely to manufacturing in small batches that sell out within six months. Freshness is the key. Taking the entire dose right before your largest meal of the day helps too.

    Many customers report improved mental clarity and reduced inflammation within 2-4 weeks. Full benefits—as measured by your Omega-3 Index—typically develop over 8-12 weeks of consistent use.

    Omega-3 is generally well-tolerated, but we recommend consulting your healthcare provider before starting any supplement, especially if you're on blood thinners or other medications.

    You’re paying for meaningful differences: higher potency (1,856 mg of omega-3s per serving vs. the 300–600 mg typical of standard fish oil), a triglyceride form shown to have higher bioavailability than ethyl esters, glass packaging, and verified third-party testing. Standard fish oil supplements may require more capsules to match this dose, and many use the ethyl ester form, which research shows is absorbed less efficiently.

    The Omega-3 Index measures the percentage of EPA and DHA in your red blood cell membranes. Research suggests an index of 8-12% is optimal for cardiovascular protection. Most Americans sit around 4-5%. Our dosing is designed to help you reach the optimal range over 8-12 weeks.

    Store in a cool, dry place. Refrigeration isn't required but can help maximize freshness and potency, especially in warmer climates.

    *Cited Sources

    REDUCE-IT Trial (2019) - 4g EPA reduced CV events by 25%

    https://www.nejm.org/doi/full/10.1056/NEJMoa1812792

    Cochrane Review (2020) - Meta-analysis confirms triglyceride reduction

    https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003177.pub5/full

    Circulation Research (2021) - Improved arterial stiffness measures

    https://www.ahajournals.org/journal/circres

    Journal of Hypertension (2019) - Significant pulse wave velocity improvements

    https://journals.lww.com/jhypertension/

    AHA Scientific Advisory (2019) - Official recommendation for fish consumption

    https://www.ahajournals.org/doi/10.1161/CIR.0000000000000709

    Frontiers in Aging Neuroscience - DHA comprises 10-20% of brain fatty acids

    https://www.frontiersin.org/journals/aging-neuroscience

    AJCN Systematic Review (2022) - Mixed results depending on baseline status

    https://academic.oup.com/ajcn

    Progress in Retinal and Eye Research - DHA is most abundant fatty acid in retinal photoreceptors

    https://www.sciencedirect.com/journal/progress-in-retinal-and-eye-research

    AREDS2 Study (NEI) - Omega-3 supplementation in eye disease

    https://www.nei.nih.gov/research/clinical-trials/age-related-eye-disease-studies-aredsareds2

    Cornea Journal (2019) - Omega-3 improved dry eye symptoms

    https://journals.lww.com/corneajrnl/

    Annals of Rheumatic Diseases - Meta-analysis of omega-3 in rheumatoid arthritis

    https://ard.bmj.com/

    Journal of Cosmetic Dermatology (2020) - Improved skin barrier function and hydration

    https://onlinelibrary.wiley.com/journal/14732165

    British Journal of Dermatology - Omega-3 increased minimal erythema dose

    https://academic.oup.com/bjd

    Translational Psychiatry (2019) - Meta-analysis shows modest antidepressant effects

    https://www.nature.com/tp/

    Journal of Leukocyte Biology - Omega-3 effects on immune cell membranes and signaling

    https://jlb.onlinelibrary.wiley.com/

    NHANES Dietary Data (CDC) - Average seafood consumption approximately 0.5 oz/day

    https://www.cdc.gov/nchs/nhanes/

    Omega-3 Index Research - Studies show most Americans below optimal levels

    https://www.omegaquant.com/omega-3-index/

    Prostaglandins Leukot Essent Fatty Acids - TG form shows 50% higher plasma levels than EE

    https://www.sciencedirect.com/journal/prostaglandins-leukotrienes-and-essential-fatty-acids

    Your Body Can't Make Omega-3s. It's Waiting For You to Provide Them.

    Every cell membrane in your body incorporates fatty acids. Your heart, brain, eyes, and immune system all depend on adequate omega-3 levels to function optimally.

    The research is clear. The deficiency is real. The solution is simple.

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